PECARN logo - Conducting High Priority, High-Quality Research in Pediatric Emergency Care


Studies Currently Enrolling

ED-STARS (Emergency Dept. Screen for Teens at Risk for Suicide)

Biosignatures II

Research Awards and Publications

The American College of Emergency Physicians (ACEP) recognized the PECARN FLUID article titled, "Clinical Trial of Fluid Infusion Rates for Pediatric Diabetic Ketoacidosis," as one of the 10 Best Medical Journal Articles from 2018. See the ACEP website for more details.


The In-Hospital THAPCA Trial paper was published on January 24, 2017 in the New England Journal of Medicine. It was the largest pediatric clinical trial conducted to study temperature management after cardiac arrest. The design of this study began in the early 2000s and enrollment was between 2009-2015.

Thank you to everyone from the division of pediatric critical care who over the years had a part – small or large - in the protocol development, database creation & validation, data cleaning, project management, in-person training sessions, medical monitoring, subject enrollment and follow-up, statistical analysis, and manuscript preparation. It was certainly a team effort. Thank you!


Annual Scientific Grant Writing Workshop

This is a valuable workshop for grant writers who want to improve their skills and receive guidance on research oriented grant writing.

This year's workshop will be held on AUGUST 27-29, 2019 in CHICAGO, IL.

Attendees will work on each section of their research grant proposal, receive continual feedback from experienced grant writers, and leave with a well-defined draft.

Visit for online registration.


Performance Measures toolbox

Training module for investigators

Recent Publications

Marcin JP, Romano PS, Dharmar M, Chamberlain JM, Dudley N, Macias CG, Nigrovic LE, Powell EC, Rogers AJ, Sonnett M, Tzimenatos L, Alpern ER, Andrews-Dickert R, Borgialli DA, Sidney E, Casper C, Dean JM, Kuppermann N, for the Pediatric Emergency Care Applied Research Network. Implicit Review Instrument to Evaluate Quality of Care Delivered by Physicians to Children in Emergency Departments. Health Serv Res. EPub 2017 Nov 16. PubMed PMID: 29143331.

Goldberg H, Paterno M, Grundmeier R, Rocha B, Hoffman J, Than E, Swietlik M, Schaeffer MH, Pabbathi D, Deakyne S, Kuppermann N, Dayan PS, for PECARN. Use of Remote Clinical Decision Support Service for a Multicenter Trial to Implement Prediction Rules for Children with Minor Blunt Head Trauma. Int J Med Inform. 2016 Mar;87:101-10. Epub 2015 Dec 4. PubMed PMID: 26806717.

Cruz AT, Mahajan P, Bonsu BK, Bennett JE, Levine DA, Alpern ER, Nigrovic LE, Atabaki SM, Cohen DM, vanBuren JM, Ramilo O, and Kuppermann N, for the Febrile Infant Working Group of the Pediatric Emergency Care Applied Research Network (PECARN). Accuracy of Complete Blood Cell Counts to Identify Febrile Infants 60 Days or Younger with Invasive Bacterial Infections. JAMA Pediatr. 2017 Nov 6;171(11):e172927. Epub 2017 Nov 6. PubMed PMID: 28892537.

Powell EC, Mahajan PV, Roosevelt G, Hoyle JD Jr, Gattu R, Cruz AT, Rogers AJ, Atabaki SM, Jaffe DM, Casper TC, Ramilo O, Kuppermann N, for the Febrile Infant Working Group of the Pediatric Emergency Care Applied Research Network (PECARN). Epidemiology of Bacteremia in Febrile Infants Aged 60 Days and Younger. Ann Emerg Med. Epub 2017 Oct 6. PubMed PMID: 28988964.

PECARN, the Pediatric Emergency Care Applied Research Network, is the first federally-funded pediatric emergency medicine research network in the United States. PECARN conducts high-priority, multi-institutional research on the prevention and management of acute illnesses and injuries in children and youth of all ages.

PECARN is supported by cooperative agreements between seven academic medical centers and the Health Resources Services Administration / Maternal and Child Health Bureau / Emergency Medical Services for Children Program (HRSA / MCHB / EMSC).